Peptide library
85 profiles of peptides and closely related compounds. Filter by research area or by the strength of the evidence. Every profile shows regulatory status first.
85 of 85 compounds
- Small-molecule NNMT inhibitor 5-Amino-1MQ 5-Amino-1MQ is a small molecule that blocks nicotinamide N-methyltransferase (NNMT), an enzyme that is overexpressed in the fat tissue of obese animals. Animal studies
- Endogenous tetrapeptide Ac-SDKP (TB fragment 1-4) Ac-SDKP is a natural tetrapeptide cut from the N-terminus of thymosin beta-4. Animal studies
- Soluble activin receptor fusion protein ACE-031 ACE-031 is a decoy receptor that binds myostatin and related growth factors. Human RCTs
- Vascular-targeted pro-apoptotic peptide Adipotide Adipotide is an experimental peptide designed to kill the blood vessels that feed white fat. Animal studies
- AMPK activator AICAR AICAR is a nucleoside that cells convert into an AMP mimic, activating AMP-activated protein kinase (AMPK), the cell’s energy sensor. Animal studies
- Modified growth hormone fragment AOD-9604 AOD-9604 is a 16-residue fragment from the C-terminal end of human growth hormone, developed in Australia as an anti-obesity drug. Early human data
- EPO-derived tissue-protective peptide ARA-290 ARA-290 is an 11-amino-acid peptide modelled on part of erythropoietin. Human RCTs
- Relaxin receptor agonist B7-33 B7-33 is a simplified, single-chain version of the hormone relaxin-2, designed to keep relaxin’s anti-fibrotic effects while being easier to make. Animal studies
- Synthetic pentadecapeptide BPC-157 BPC-157 is a synthetic 15-amino-acid peptide studied mainly for tendon, ligament, muscle and gut healing in rodents. Animal studies
- Multi-peptide blend BPC-157 + TB-500 blend This blend combines BPC-157 and TB-500 (thymosin beta-4 or its fragment) in one vial, usually in equal amounts by mass. Animal studies
- Short peptide bioregulator Bronchogen Short peptide described as a bioregulator of the bronchial epithelium. Animal studies
- Long-acting amylin analog Cagrilintide Cagrilintide is a long-acting amylin analog that acts on both amylin and calcitonin receptors. Human RCTs
- Short peptide bioregulator Cardiogen Short peptide described as a bioregulator of the heart muscle. Animal studies
- Short peptide bioregulator Cartalax Short peptide described as a bioregulator of the cartilage. Animal studies
- Porcine brain-derived peptide mixture Cerebrolysin Cerebrolysin is a mixture of low-molecular-weight peptides and amino acids derived from pig brain proteins. Approved medicine
- Short peptide bioregulator Chonluten Short peptide described as a bioregulator of the bronchial and gastric mucosa. Animal studies
- GHRH analog CJC-1295 (no DAC) CJC-1295 without DAC, also called Modified GRF (1-29), is sermorelin with four amino acid substitutions that make it more resistant to breakdown. Animal studies
- Long-acting GHRH analog CJC-1295 (with DAC) CJC-1295 with DAC is a modified GHRH analog that attaches itself to albumin in the blood, extending its half-life to about six to eight days. Early human data
- Multi-peptide blend CJC-1295 + Ipamorelin blend This blend pairs a GHRH analog (usually CJC-1295 without DAC) with the ghrelin-receptor agonist ipamorelin. Animal studies
- Short peptide bioregulator Cortagen Short peptide described as a bioregulator of the cerebral cortex. Animal studies
- Short peptide bioregulator Crystagen Short peptide described as a bioregulator of the immune system. Animal studies
- Angiotensin IV analog Dihexa Dihexa is a small, orally active angiotensin IV analog developed at Washington State University. Animal studies
- Neuropeptide DSIP DSIP is a nine-residue peptide isolated in 1977 from rabbits in which slow-wave sleep had been induced by electrical brain stimulation. Early human data
- Short peptide bioregulator Epitalon Epitalon is a four-amino-acid peptide developed by Vladimir Khavinson’s group as a synthetic version of a pineal gland extract. Animal studies
- Myostatin-binding glycoprotein Follistatin-344 Follistatin is a natural protein that binds and neutralizes myostatin and activin, two signals that limit muscle growth. Early human data
- Senolytic D-retro-inverso peptide FOXO4-DRI FOXO4-DRI is a modified peptide designed to disrupt the interaction between FOXO4 and p53 in senescent cells, pushing those cells into apoptosis. Animal studies
- Tripeptide GHK (copper-free) GHK without copper is the free tripeptide. Cell studies
- Copper-binding tripeptide GHK-Cu GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva and urine. Early human data
- Ghrelin-receptor agonist GHRP-2 GHRP-2 is a hexapeptide ghrelin-receptor agonist and one of the most potent GH releasers in its class. Approved medicine
- Ghrelin-receptor agonist GHRP-6 GHRP-6 is a synthetic hexapeptide described by Cyril Bowers in 1984 that releases growth hormone through what was later identified as the ghrelin receptor. Early human data
- Multi-peptide blend GLOW blend GLOW is a supplier name for a three-part vial of GHK-Cu, BPC-157 and TB-500, marketed for skin and tissue repair. Animal studies
- Antioxidant tripeptide Glutathione Glutathione is the main intracellular antioxidant, a tripeptide made by nearly every cell. Human RCTs
- Gonadotropin-releasing hormone Gonadorelin Gonadorelin is synthetic GnRH, identical to the natural hypothalamic hormone. Approved medicine
- Glycoprotein hormone hCG Human chorionic gonadotropin is the hormone that pregnancy tests detect. Approved medicine
- Ghrelin-receptor agonist Hexarelin Hexarelin is a methylated analog of GHRP-6 that releases growth hormone after injection, nasal or oral administration in people. Early human data
- Growth hormone fragment HGH Fragment 176-191 HGH Fragment 176-191 is the supplier name for a C-terminal growth hormone fragment that is essentially the same molecule as AOD-9604. Animal studies
- Mitochondrial-derived peptide Humanin Humanin is a 24-amino-acid peptide discovered in 2001 in a screen for factors that protect neurons from Alzheimer’s-related cell death. Animal studies
- IGF-1 analog IGF-1 LR3 IGF-1 LR3 is an engineered form of insulin-like growth factor 1 that binds poorly to IGF-binding proteins, so more of it stays free to act on the IGF-1 receptor. Cell studies
- Selective ghrelin-receptor agonist Ipamorelin Ipamorelin is a five-residue ghrelin-receptor agonist described in 1998 as the first selective growth hormone secretagogue. Human RCTs
- Reproductive neuropeptide Kisspeptin-10 Kisspeptin is the master upstream signal of the reproductive axis: it triggers the hypothalamus to release GnRH, which in turn drives LH and FSH. Human RCTs
- Multi-peptide blend KLOW blend KLOW adds the anti-inflammatory tripeptide KPV to the three components of GLOW. Animal studies
- Anti-inflammatory tripeptide KPV KPV is the C-terminal tripeptide of alpha-MSH and carries much of that hormone’s anti-inflammatory activity without its pigment effects. Animal studies
- GLP-1 receptor agonist Liraglutide Liraglutide was the first once-daily GLP-1 receptor agonist and the predecessor of semaglutide. Approved medicine
- Short peptide bioregulator Livagen Short peptide described as a bioregulator of the liver. Animal studies
- Human antimicrobial peptide LL-37 LL-37 is the only human cathelicidin, an antimicrobial peptide made by skin, gut and immune cells. Human RCTs
- GLP-1 and glucagon receptor agonist Mazdutide Mazdutide is a once-weekly dual agonist of the GLP-1 and glucagon receptors, modelled on the gut hormone oxyntomodulin. Approved medicine
- MC1R agonist (α-MSH analog) Melanotan I Melanotan I is afamelanotide, a stabilized analog of alpha-MSH. Approved medicine
- Non-selective melanocortin agonist Melanotan II Melanotan II is a synthetic cyclic peptide developed at the University of Arizona in the 1990s as a sunless tanning agent. Early human data
- IGF-1 splice-variant peptide MGF and PEG-MGF MGF refers to a peptide from the unique tail of IGF-1Ec, a form of IGF-1 produced by muscle after mechanical stress. Cell studies
- Oral non-peptide ghrelin-receptor agonist MK-677 MK-677 (ibutamoren) is an orally active small molecule that mimics ghrelin and raises growth hormone and IGF-1. Human RCTs
- Mitochondrial-derived peptide MOTS-c MOTS-c is a 16-amino-acid peptide encoded by mitochondrial DNA, discovered in 2015. Animal studies
- Multi-peptide blend MOTS-c + Humanin blend This blend combines two mitochondrial-derived peptides. Animal studies
- Coenzyme NAD+ NAD+ is a coenzyme present in every living cell, essential for energy metabolism and for enzymes such as sirtuins and PARPs. Early human data
- Oral small-molecule GLP-1 receptor agonist Orforglipron Orforglipron is a once-daily oral GLP-1 receptor agonist that is a small molecule rather than a peptide, so it needs no injection and no fasting before dosing. Approved medicine
- Short peptide bioregulator Ovagen Short peptide described as a bioregulator of the liver and gastrointestinal tract. Animal studies
- Neurohypophyseal hormone Oxytocin Oxytocin is a nine-amino-acid hormone made in the hypothalamus. Approved medicine
- Short peptide bioregulator Pancragen Short peptide described as a bioregulator of the pancreas. Animal studies
- TREK-1 channel blocker PE-22-28 PE-22-28 is a shortened analog of spadin, a natural peptide that blocks the TREK-1 potassium channel. Animal studies
- Short peptide bioregulator Pinealon Short peptide described as a bioregulator of the brain and nervous tissue. Animal studies
- Short peptide bioregulator Prostamax Short peptide described as a bioregulator of the prostate. Animal studies
- Melanocortin receptor agonist PT-141 PT-141 (bremelanotide) is a cyclic melanocortin agonist approved by the FDA in 2019 as Vyleesi, an on-demand injection for low sexual desire in premenopausal women. Approved medicine
- GIP, GLP-1 and glucagon receptor agonist Retatrutide Retatrutide is an investigational triple agonist of the GIP, GLP-1 and glucagon receptors. Human RCTs
- Tuftsin analog Selank Selank is a synthetic seven-residue analog of tuftsin, a fragment of immunoglobulin G. Early human data
- Multi-peptide blend Selank + Semax blend This blend pairs the two Russian-developed heptapeptides, Selank (studied for anxiety) and Semax (studied for stroke and cognition). Animal studies
- GLP-1 receptor agonist Semaglutide Semaglutide is a long-acting GLP-1 receptor agonist approved for type 2 diabetes, chronic weight management and cardiovascular risk reduction. Approved medicine
- ACTH(4-10) analog Semax Semax is a seven-amino-acid peptide developed in Russia from a fragment of adrenocorticotropic hormone (ACTH). Early human data
- GHRH analog Sermorelin Sermorelin is the active 29-amino-acid fragment of growth-hormone-releasing hormone. Approved medicine
- MC4R agonist Setmelanotide Setmelanotide is a selective MC4R agonist approved for rare genetic forms of obesity in which the brain’s leptin–melanocortin pathway is broken. Approved medicine
- Small-molecule ERR agonist SLU-PP-332 SLU-PP-332 is a synthetic agonist of the estrogen-related receptors (ERRα, β and γ) developed at Saint Louis University. Animal studies
- Cosmetic neurotransmitter-modulating peptide SNAP-8 SNAP-8 is a cosmetic peptide marketed to reduce expression lines by mimicking part of the SNAP-25 protein. Early human data
- Cardiolipin-targeting tetrapeptide SS-31 SS-31, now the approved drug elamipretide, is a four-residue peptide that binds cardiolipin in the inner mitochondrial membrane. Approved medicine
- GLP-1 and glucagon receptor agonist Survodutide Survodutide is an investigational once-weekly dual agonist of the glucagon and GLP-1 receptors, studied for obesity and fatty liver disease. Human RCTs
- Thymosin beta-4 peptide TB-500 TB-500 is the trade name for synthetic thymosin beta-4 or its active fragment. Early human data
- GHRH analog Tesamorelin Tesamorelin is a stabilized form of growth-hormone-releasing hormone. Approved medicine
- Short peptide bioregulator Testagen Short peptide described as a bioregulator of the testes. Animal studies
- Thymus-derived peptide complex Thymalin Thymalin is a mixture of polypeptides extracted from calf thymus, registered in Russia as an immune-modulating medicine. Early human data
- Short peptide bioregulator Thymogen Short peptide described as a bioregulator of the immune system. Animal studies
- Thymic immunomodulatory peptide Thymosin Alpha-1 Thymosin alpha-1 is a 28-amino-acid peptide from the thymus that modulates T-cell and dendritic-cell function. Approved medicine
- Zinc-dependent thymic nonapeptide Thymulin Thymulin is a nine-residue hormone secreted by thymic epithelial cells that needs zinc to be active. Animal studies
- GIP and GLP-1 receptor agonist Tirzepatide Tirzepatide activates both the GIP and GLP-1 receptors. Approved medicine
- GnRH agonist Triptorelin Triptorelin is a long-acting GnRH agonist. Approved medicine
- Short peptide bioregulator Vesilute Short peptide described as a bioregulator of the bladder and urinary tract. Animal studies
- Short peptide bioregulator Vesugen Short peptide described as a bioregulator of the blood vessel walls. Animal studies
- Short peptide bioregulator Vilon Short peptide described as a bioregulator of the immune system and thymus. Animal studies
- Neuropeptide VIP Vasoactive intestinal peptide is a 28-amino-acid neuropeptide found throughout the gut, lungs, brain and immune system. Approved medicine
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