Summary
This blend combines two mitochondrial-derived peptides. Both have been studied separately in metabolic and ageing models in animals, and neither has completed controlled human trials.
Components
- Mitochondrial-derived peptide MOTS-c MOTS-c is a 16-amino-acid peptide encoded by mitochondrial DNA, discovered in 2015. Animal studies
- Mitochondrial-derived peptide Humanin Humanin is a 24-amino-acid peptide discovered in 2001 in a screen for factors that protect neurons from Alzheimer’s-related cell death. Animal studies
How it works
Both peptides are encoded in mitochondrial DNA and have overlapping roles in cellular stress responses and insulin sensitivity in animal models.
Research use cases
Areas where MOTS-c + Humanin blend has been studied. Inclusion here does not mean it works for that purpose.
- Combines the research areas of its components; see each component profile
What the research found
No combination studies
We found no published peer-reviewed study testing this exact combination in animals or people. Evidence comes only from studies of each component on its own.
Safety and open questions
Combining compounds can change how each behaves, and fixed ratios mean you cannot adjust one without the other. Component purity and identity are harder to verify in a blend, because a single certificate of analysis must confirm several peptides.
Regulatory status
Not approved. A supplier-defined combination; no regulator has evaluated it.
Status was accurate when this page was last reviewed on October 26, 2026. Regulations change; check with the relevant authority before relying on it.
MOTS-c + Humanin blend: common questions
How do I calculate amounts for a blend?
All components dissolve into the same water, so every draw contains them in the same ratio as the vial. Use the blend calculator, which shows the amount of each component per draw.
Is MOTS-c + Humanin blend approved for human use?
Not approved. A supplier-defined combination; no regulator has evaluated it.