Mitochondrial-derived peptide

MOTS-c reconstitution calculator

MOTS-c is commonly supplied as 5 mg, 10 mg, 40 mg vials. Pick a vial size and a water volume to see the concentration and what each syringe mark holds. Enter a target amount to see the draw. This page does not suggest any amount.

Vial contents
Diluent
Target amount per draw
Syringe

Draw to

– units

– mL on a U-100 syringe

Concentration
– mg/mL
Per 1 unit
– mcg
Draws per vial
–
Total in vial
– mcg
What each mark on the syringe holds
UnitsmLContains

About MOTS-c

MOTS-c is a 16-amino-acid peptide encoded by mitochondrial DNA, discovered in 2015. It acts mainly on skeletal muscle, where it improves insulin sensitivity. In mice it prevented diet-induced obesity and, in older animals, improved physical capacity. Blood levels rise with exercise in people.

Read the full MOTS-c profile

MOTS-c calculator questions

How much bacteriostatic water do I add to a 5 mg MOTS-c vial?

The calculator does not prescribe a volume; the right choice depends on how large you want each draw to be. As arithmetic: 5 mg in 2 mL gives 2.5 mg/mL, so each unit on a U-100 syringe holds 25 mcg. Use the “Water to add” tab to work backwards from a draw size.

What concentration does MOTS-c have after reconstitution?

Concentration is the vial mass divided by the water volume. For example, 5 mg in 2 mL is 2.5 mg/mL. Check the certificate of analysis for net peptide content, which is usually lower than the label.

Where can I read the research on MOTS-c?

See the MOTS-c research profile for mechanism, study findings, safety and regulatory status, with references.